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P A R T N E R S O C I E T I E S V I E W Dr. John Wells discusses anti-VEGFs for DME View Dr. Soosan Jacob performs cataract surgery in a patient with an intraocular foreign body View R E A D Dr. Seenu Hariprasad discusses risk factors for RPE tears after ranibizumab for RAP Read D I S C U S S EHR system user reviews Sign up for weekly Forum and discussion updates Follow the Academy You may offer a free subscription of this publication to a colleague. NEW JOURNAL STUDIES Statins don’t protect against AMD progression 3D-derived ‘super formula’ improves IOL calculations Don’t base blow-out fracture surgical decisions on radiological findings Contrast sensitivity key to glaucoma patients’ quality of life Phaco combined with gel stent appears effective for IOP reduction NEW JOURNAL STUDIES FROM AUSTRALIA AND NEW ZEALAND (RANZCO) Ibopamine challenge test can diagnose glaucoma stages Brilliant Blue G appears safe for retinal cells NEWS FROM AUSTRALIA AND NEW ZEALAND (RANZCO) RANZCO Leadership Development Program 2016-2017 RANZCO Social Media: Join the discussion ACADEMY NEWS Now open: Instruction course abstract submitter Study for the OKAP with confidence ‘Tis the season for giving back NEW JOURNAL STUDIES Statins don’t protect against AMD progression This evaluation of data from AREDS2 found no significant association between statin use and progression to late AMD, which confirms previously published studies. AREDS2 included 1,329 patients with late AMD at baseline, and more than 40% of participants were statin users. Because statins have been shown to reduce the risk of cardiovascular disease, AMD patients should be encouraged to take them when medically indicated, but they should be monitored regularly for progression of AMD regardless of statin use. Ophthalmology, December 2015 3D-derived ‘super formula’ improves IOL calculations Using computer-generated 3D surfaces based on 6 common IOL calculation formulas, the authors determined the points at which the IOL powers from each formula showed the greatest difference, and then generated a 3D “super surface” incorporating the most accurate portions of each formula to form one super formula. Tested in 100 eyes, the super formula calculated the most accurate IOL power value in all eyes. In comparison, the individual formulas deviated from the optimal super formula IOL power values by more than 0.5 D 30% of the time in Hoffer Q, 16% in Holladay I, 22% in Holladay I with Koch adjustment, 48% in Haigis and 24% in SRK/T. JAMA Ophthalmology, December 2015 Don’t base blow-out fracture surgical decisions on radiological findings The authors assessed the accuracy of computed tomography (CT) image readings in an everyday setting by measuring the variability among 3 trained neuroradiologists who reviewed images for 23 patients with isolated orbital fractures. In their evaluation, the authors found only moderate agreement for anterior to posterior length (0.66) and for transverse width (0.44). Based on this variability, the authors question whether physicians should rely on the current 50% floor fracture criterion and urge them instead to base their surgical decisions on clinical findings. JAMA Ophthalmology, December 2015 Contrast sensitivity key to glaucoma patients’ quality of life This prospective study evaluated the relationships between clinical visual assessments, vision-related performances, and subjective vision-related quality of life over a period of 4 years. Subjects included 161 patients with moderate glaucoma. The authors found the strongest correlation was between contrast sensitivity in the better eye and an objective measure of the ability to perform vision-related activities (r=0.398; P<0.001). Contrast sensitivity and visual field were associated with both objective measures of ability to act and subjective measurements of vision-related quality of life. JAMA Ophthalmology, December 2015 Phaco combined with gel stent appears effective for IOP reduction This prospective trial evaluated 2 models of an ab interno gelatin stent (Xen140 and Xen63) implanted during cataract surgery without mitomycin C. Subjects included 37 patients (37 eyes) with a mean preop IOP of 22.4 mm Hg. At 1 year postop, IOP decreased by a mean of 7.0 mm Hg, with a mean reduction of 1.6 medications (P<.0001). The gel implant is a new device that shunts aqueous from the anterior chamber to the subconjunctival space. No patient required additional glaucoma surgery and all cataract surgeries were uneventful. Journal of Cataract & Refractive Surgery, September 2015 Back to Top NEWS FROM AUSTRALIA AND NEW ZEALAND (RANZCO) RANZCO Leadership Development Program 2016-2017 The Royal Australian and New Zealand College of Ophthalmologists (RANZCO) is calling for expressions of interest from RANZCO Fellows who wish to participate in the RANZCO Leadership Development Program 2016-2017. The RANZCO Leadership Development Program (LDP) is part of RANZCO's charter to build leadership and advocacy skills within its Fellows. It aims to support ophthalmologists who work for the greater good of the community and ophthalmology as a profession, and to develop the next generation of ophthalmic leaders. Find more information online. RANZCO Social Media: Join the discussion RANZCO is expanding its social media presence. Like us on Facebook and follow us on Twitter, and join the discussion. Back to Top NEW JOURNAL STUDIES FROM AUSTRALIA AND NEW ZEALAND (RANZCO) Ibopamine challenge test can diagnose glaucoma stages This non-randomized clinical trial assessed the efficacy of 2% ibopamine, a topical drug that temporarily increases aqueous production, for diagnosing glaucoma. After instillation, IOP and optic cup volume (OCV) were measured. The authors found that glaucoma suspects could be differentiated by their IOP response from patients with stable glaucoma (SG) and patients who demonstrated rapid progression (PG). Additionally, SG patients could be differentiated from PG patients by their change in OCV following an ibopamine challenge. Clinical and Experimental Ophthalmology, December 2015 Brilliant Blue G appears safe for retinal cells Investigators evaluated the safety profile of Brilliant Blue G (BBG) on 3 retinal cell lines, retinal pigment epithelial cells, neurosensory retinal cells and Müller cells. Cells were treated with BBG (0.5x, 1x and 2x clinical concentrations) with or without surgical illumination of halogen light exposure for 10 min, 15 min or 30min. The authors found that exposure to BBG dye at clinical concentrations (0.125mg/mL and 0.25mg/mL) in the presence up to 30 minutes of surgically equivalent light intensity is safe for retinal cells. Clinical and Experimental Ophthalmology, December 2015 Back to Top ACADEMY NEWS Now open: Instruction course abstract submitter Submit an abstract for an instruction course for AAO 2016, which will be held in conjunction with the Asia-Pacific Academy of Ophthalmology. The abstract submission deadline is Jan. 12. The meeting takes place in Chicago from Oct. 15 to 18. View submission guidelines and more information online. Study for the OKAP with confidence Prepare for the 2016 OKAP (Ophthalmic Knowledge Assessment Program) exam with Provision®: Ophthalmic Multiple-Choice Questions with Discussions, Series 5. This Academy resource contains 550 multiple-choice questions and discussions of preferred responses, numerous images and suggested resources for further study. Purchase from the Academy store. ‘Tis the season for giving back As you wrap up the year, consider making a tax-deductible gift to the Academy Foundation by Dec. 31. It’s the perfect time to recognize a mentor, colleague or family member by making a charitable contribution in their honor. Your gift will help fund the Academy’s educational, quality-of-care and service programs. Member support is vital to the success of programs like the ONE Network, Global Outreach and EyeCare America, which help ophthalmologists worldwide to protect sight and empower lives. Back to Top ASIA PACIFIC ADVISORY PANEL: Asia Pacific Academy of Ophthalmology (APAO): Dr. Raj V. Azad Royal Australian and New Zealand College of Ophthalmologists (RANZCO): Drs. Heather Mack and Ralph Higgins Cambodian Ophthalmological Society (COS): Drs. Ngy Meng and Mar Amarin Chinese Ophthalmological Society (COS): Dr. Xiaoxin Li All India Ophthalmological Society (AIOS): Drs. S. Natarajan and D. Ramamurthy Indonesian Ophthalmologist Association (PERDAMI): Drs. Ari Djatikusumo and Tjahjono D. Gondhowiardjo Japanese Ophthalmological Society (JOS): Dr. Takeshi Yoshitomi, MD, PhD Korean Ophthalmological Society (KOS): Drs. Young Joon Jo and Min Ahn Malaysian Society of Ophthalmology (MSO): Dr. Tara Mary George Mongolian Ophthalmological Society (MOS): Drs. Chimgee Chuluunkhuu and Batchimeg Battumur Nepal Netra Jyoti Sangh (NNJS): Dr. Ram Prasad Pokhrel Pacific Eye Care Society (PacEYES): Drs. Rabebe Tekeraoi and Mundi Qalo Philippine Academy of Ophthalmology (PAO): Drs. Harvey Uy and Franz Marie Cruz College of Ophthalmologists of Sri Lanka (CSOL): Drs. Deepanee Wewalwalwala and Manel Pasqual Ophthalmological Society of Taiwan (TOS): Drs. Ching-Yao Tsai and Po-Ting Yeh Taiwanese Society of Cataract and Refractive Surgeons (TSCRS): Drs. Tetsaw Chen and David Chaokai Chang Royal College of Ophthalmologists of Thailand (RCOPT): Drs. Pornchai Simaro, Yosanan Yospaiboon Editor-in-Chief: Dr. David W. Parke II Chief Medical Editor: Dr. Philip R. Rizzuto Managing Editor: Susanne Medeiros AAO Advisory Panel: Drs. Terry L. Forrest, Jean E. Ramsey, Milam A. Brantley, James C. Tsai, Sunita Radhakrishnan CONTACT INFORMATION Asia Pacific Academy of Ophthalmology (APAO): secretariat@APAOphth.org Royal Australian and New Zealand College of Ophthalmologists (RANZCO): ranzco@ranzco.edu Cambodian Ophthalmological Society (COS: doseiha@gmail.com Chinese Ophthalmological Society (COS): cenbj@public3.bta.net.cn All India Ophthalmological Society (AIOS): secretary@aios.org Indonesian Ophthalmologist Association (PERDAMI): perdami@indo.net.id Japanese Ophthalmological Society (JOS): jos2@po.nichigan.or.jp Korean Ophthalmological Society (KOS): kos@ophthalmology.org Malaysian Society of Ophthalmology (MSO): msophth@gmail.com Mongolian Ophthalmological Society (MOS): info@mon-ophth.mn Nepal Netra Jyoti Sangh (NNJS): kath@nnjs.wlink.com.np Pacific Eye Care Society (PacEYES): peifiji@gmail.com Philippine Academy of Ophthalmology (PAO): secretariat_pao@globelines.com.ph College of Ophthalmologists of Sri Lanka (CSOL): ophsleye@gmail.com Ophthalmological Society of Taiwan (TOS): oph4@oph.org.tw Taiwanese Society of Cataract and Refractive Surgeons (TSCRS): mail@tscrs.org.tw Royal College of Ophthalmologists of Thailand (RCOPT): admin@rcopt.org The Academy provides the items appearing in the Academy Express as a service to AAO, AIOS, COS, CSOL, JOS, MOS, MSO, NNJS, PAO, PERDAMI, RANZCO, RCOPT, TOS and TSCRS members. The articles and studies come from news reports and peer-reviewed journals, and are not the product, opinion or position of the Academy unless explicitly stated to be so. The Academy does not endorse products, companies or organizations. The Academy disclaims all liability. If you would like to update your email address, ask a question or be removed from the mailing list, send a request to the Academy. ©2015 American Academy of Ophthalmology. All rights reserved. American Academy of Ophthalmology 655 Beach Street | San Francisco, CA 94109 Phone: +1 415.561.8500 | Fax: +1 415.561.8575 | www.aao.org